Ivermectin

With oral use:

Ivermectin is used for the treatment of onchocerciasis, but is not licensed for this indication.

Some people have and are using horse ivermectin 

General side-effects:

Common or very common

Skin reactions

Specific side-effects:

Frequency not known

With oral use

Abdominal pain; abnormal sensation in eye; anaemia; appetite decreased; arthralgia; asthenia; asthma exacerbated; coma; confusion; constipation; diarrhoea; difficulty standing; difficulty walking; dizziness; drowsiness; dyspnoea; encephalopathy; eye erythema; eye inflammation; fever; gastrointestinal disorders; haemorrhage; headache; hepatic disorders; hyperbilirubinaemia; hypereosinophilia; leucopenia; lymphatic abnormalities; Mazzotti reaction; myalgia; nausea; oedema; pain; postural hypotension; psychiatric disorder; severe cutaneous adverse reactions (SCARs); stupor; tachycardia; tremor; urinary incontinence; vertigo; vomiting

Use only if potential benefit outweighs risk—no adverse effects in limited human data (recommendation also supported by specialist sources).

With oral use:

Specialist sources indicate present in milk but amount probably too small to be harmful.

With topical use:

Caution in severe impairment (no information available).

With topical use:

Apply a pea-size amount thinly to each of the five areas of the face: forehead, chin, nose and each cheek, avoiding the eyes, lips and mucosa. Wash hands after use. Cosmetics may be applied after the cream has dried.

With oral use:

Tablets can be crushed before swallowing.

With oral use:

Patients and carers should be advised to take ivermectin on an empty stomach; 2 hours before or 2 hours after food (effect of food on absorption is unknown).