All About Ascorbic Acid

Natural vs Synthetic Ascorbic Acid
Natural and synthetic L-ascorbic acid are chemically identical, and there are no known difference in their biological activity. The possibility that the bioavailability of L-ascorbic acid from natural sources might differ from that of synthetic ascorbic acid was investigated in at least two human studies, and no clinically significant differences were observed.

Ascorbic Deficiency
The following problems should be expected with increased incidence with severe depletion of ascorbate: disorders of the immune system such as secondary infections, rheumatoid arthritis and other collagen diseases, allergic reactions to drugs, foods and other substances, chronic infections such as herpes, or sequelae of acute infections such as Guillain-Barre and Reye's syndromes, rheumatic fever, or scarlet fever, disorders of the blood coagulation mechanisms such as hemorrhage, heart attacks, strokes, hemorrhoids and other vascular thrombosis; failure to cope properly with stresses due to suppression of the adrenal functions such as phlebitis, other inflammatory disorders, asthma and other allergies; problems of disordered collagen formation such as impaired ability to heal, excessive scarring, bed sores, varicose veins, hernias, stretch marks, wrinkles, perhaps even wear of cartilage or degeneration of spinal discs; impaired function of the nervous system such as malaise, decreased pain tolerance, and cancer from suppressed immune system and carcinogens not detoxified, etc. Note: I am not saying that ascorbate depletion is the only cause of the disorders, but I am pointing out that disorders of the systems would certainly predispose to the diseases and that these systems are known to be dependent upon ascorbate for their proper function. Not only is there the theoretical probability that these types of complications associated with infections or stresses could result from ascorbate depletion, but there was a conspicuous decrease in the expected occurrence of complications in the thousands of patients treated with oral tolerance doses or intravenous doses of ascorbate. This impression of marked decrease in these problems is shared by physicians experienced with the use of ascorbate such as Klenner and KaloKerinos.

Successful Dosing
For very severe illness, the dose he used was large and the most effective route was intravenous, but the intramuscular route was satisfactory. He gave at least 350 mg per kilogram of body weight (a 70 kg man is 150 pounds; thus 70 x 350 = 24,500 mg). This amount was put in 500cc of sterile water, usually dextrose, saline or Ringer's solution. It was diluted so that there was at least 18cc of diluent to each gram of C.

Maintenance Doses
Maintenance doses are established by the patient taking bowel tolerance doses 6 times a day for at least a week. He observes if there is any unexpected benefit such as clearing of sinuses, decrease in allergies, increase in energy, etc. Should any chronic problem be benefited, then the dose is decreased to the minimum amount producing the effect. Otherwise, a dose such as 4 to 10 grams a day divided in 3-4 doses is recommended. Patients who take ascorbate in large amounts over a long period of time should probably supplement with vitamin A and multiple mineral preparation.

How to make Sodium Ascorbate
Sodium Ascorbate is a buffered form of Vitamin C that consists of 90% Ascorbic Acid bound to 10% Sodium. This is the optimal form of Vitamin C for intravenous injection. So, if you have 100 grams of ascorbic acid then you would need 10 grams of baking soda, then add distilled water--so your ratio is 9:1. When adding water this mixture will begin to fizz. Mix gently until fizzing stops. What you have left is sodium ascorbate.

Formula
-8 grams of Ascorbic Acid
-500mgs of potassium bicarb
-sodium bicarbonate
-magnesium citrate
-30 mgs of zinc

Generally, the ratios are almost 100-160:10 or thereabouts

This will allow for better uptake of the minerals and the buffered C